wwl70

Item no.	V17481-50mg
Manufacturer	InvivoChem LLC
CASRN	947669-91-2
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V17481CAS #:947669-91-2Purity >=98% Description: WWL-70 is a novel, potent inhibitor of alpha/beta-hydrolase domain 6 (ABHD6) with IC50 of 70 nM. alpha/beta-hydrolase domain 6 is an enzyme which catalyzes the hydrolysis of 2-arachidonylglycerol. References: 1. LiW, et al. A functional proteomic strategy to discover inhibitors foruncharacterized hydrolases. J Am Chem Soc. 2007 Aug 8; 129(31):9594-5. 2. TanakaM, et al. WWL70 attenuates PGE2 production derived from2-arachidonoylglycerol in microglia by ABHD6-independent mechanism. JNeuroinflammation. 2017 Jan 10; 14(1):7. 3. TchantchouF, et al. Selective inhibition of alpha/beta-hydrolase domain 6attenuates neurodegeneration, alleviates blood brain barrier breakdown, and improves functional recovery in a mouse model of traumatic braininjury. J Neurotrauma. 2013 Apr 1; 30(7):565-79. 4. Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17558-63.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50mg

available

Delivery expected until 9/6/2024

Express Delivery: Save 4 days

Compare

Add to wishlist

Recommend by mail