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mexiletine-hcl

mexiletine-hcl

Item no.	V1657-1g
Manufacturer	InvivoChem LLC
CASRN	5370-01-4
Amount	1g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1657CAS #:5370-01-4Purity >=98% Description: Mexiletine HCl (KO1173), belongs to Class IB anti-arrhythmic group of medications used to treat abnormal heart rhythms, chronic pain, and some causes of muscle stiffness, is a non-selective voltage-gated sodium channel blocker that inhibits sodium channels to reduce the inward sodium current. Mexiletine is a local anesthetic, antiarrhythmic agent (Class Ib), structurally similar to lidocaine, but orally active. Mexiletine, inhibits the inward sodium current required for the initiation and conduction of impulses, thus reducing the rate of rise of the action potential. It achieves this reduced sodium current by inhibiting sodium channels. References: Curr Med Chem. 2015; 22(11):1400-13; Curr Pain Headache Rep. 2010 Apr; 14(2):145-50. Related CAS #:31828-71-4 (free) 5370-01-4 (HCl)
Molecular Weight (MW)	215.72
Formula	C11H17NO.HCl
CAS No.	5370-01-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 43 mg/mL (199.3 mM)
	Water: 43 mg/mL (199.3 mM)
	Ethanol: 43 mg/mL (199.3 mM)
Other info	Chemical Name: 1-(2, 6-dimethylphenoxy)propan-2-amine hydrochloride InChi Key: NFEIBWMZVIVJLQ-UHFFFAOYSA-N InChi Code: InChI=1S/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12; /h4-6, 10H, 7, 12H2, 1-3H3; 1H SMILES Code: CC(N)COC1=C(C)C=CC=C1C.[H]Cl
Synonyms	KO1173; Mexiletine, Mexitil, Mexiletene, KO-1173, KO 1173

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Amount: 1g

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Delivery expected until 9/6/2024