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Description: Nefopam HCl (Fenazoxine) is a potent and centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake. It is widely used for the relief of moderate to severe pain as an alternative to opioid analgesic drugs. The mechanism of analgesia is not completely understood, it appears that nefopam is a centrally acting, non-opioid analgesic that inhibits reuptake of serotonin, norepinephrine, and dopamine.
References: Br J Anaesth. 2008 Nov; 101(5):610-7.
Related CAS #: 13669-70-0 (free base) 23327-57-3 (HCl) 46868-19-3 (N-Desmethylnefopam)
Chemical Name: 5-Methyl-1-phenyl-3, 4, 5, 6-tetrahydro-1H-2, 5-benzoxazocine hydrochloride
InChi Key: CNNVSINJDJNHQK-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18; /h2-10, 17H, 11-13H2, 1H3; 1H
SMILES Code: CN1CCOC(C2=CC=CC=C2)C3=CC=CC=C3C1.[H]Cl
Leoplexamin; Nefopam HCl; Nefopam hydrochloride; Fenazoxine hydrochloride; Lenipan; Oxadol; Pallopikeron, Brand name Acupan
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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