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Description: GSK3532795, formerly known as BMS955176, is a potent, orally bioavailable, second-generation HIV-1 maturation inhibitor (MI) that advanced through phase IIb clinical trials. GSK3532795 combines broad coverage of polymorphic viruses (EC50< 15 nM toward a panel of common polymorphisms representative of 96.5% HIV-1 subtype B virus) with a favorable pharmacokinetic profile in preclinical species.
References: J Med Chem. 2018 Aug 23; 61(16):7289-7313; PLoS One. 2018 Oct 23; 13(10):e0205368.
Related CAS #: 1392312-45-6 (free base) 2097784-79-5 (TFA) 2023808-13-9 (HCl) 2023798-97-0 (HCl hydrate) 2097784-79-5 (oxalate)
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