JavaScript seems to be disabled in your browser. You must have JavaScript enabled in your browser to utilize the functionality of this website.
Description: Canagliflozin (formerly TA-7284; JNJ-24831754ZAE; JNJ 28431754-AAA; JNJ-28431754; brand name Invokana) is a highly potent and selective SGLT2 (sodium-glucose transport protein) inhibitor with anti-diabetic activity. Canagliflozin has been approved by FDA for the treatment of type 2 diabetes. It inhibits hSGLT2 with an IC50 of 2.2 nM in a cell-free assay, and exhibits > 413-fold selectivity over hSGLT1.
References: PLoS One. 2012; 7(2):e30555; J Med Chem. 2010 Sep 9; 53(17):6355-60
Related CAS#: 928672-86-0 (hemihydrate); 842133-18-0 (free)
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
Request Data Sheet
Request product datasheet
Request safety datasheet
Compare
Add to wishlist
Recommend by mail
Get an offer
Request delivery time
Ask a technical question
Submit a bulk request
sales@hoelzel.de
« Back
Subscribe, get 15% off every fifth order and have your items delivered on time!
Forgot Your Password?
Not yet registered? Create account here!