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sjb2-043

sjb2-043

Item no.	V14847-10mg
Manufacturer	InvivoChem LLC
CASRN	63388-44-3
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V14847CAS #:63388-44-3Purity >=98% Description: SJB2-043, a C527 analog, is a novel and potent inhibitor of USP1/UAF1 (ubiquitin-specific protease 1/Usp1-associated Factor 1) complex with IC50 of 544 nM. It inhibited the Ub-VS labeling of a limited number of endogenous DUBenzymes and inhibited the labeling of USP1 with Ub-VS in a dosedependent manner. Usp1-associated Factor 1) References: 1. MistryH, et al. Small molecule inhibitors of USP1 target ID1 degradation inleukemic cells. Mol Cancer Ther. 2013 Dec; 12(12):2651-62. 2. Goncalves JM, Cordeiro MMR, Rivero ERC. The Role of the Complex USP1/WDR48 in Differentiation and Proliferation Processes in Cancer Stem Cells. Curr Stem Cell Res Ther. 2017; 12(5):416-422.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

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