JavaScript seems to be disabled in your browser. You must have JavaScript enabled in your browser to utilize the functionality of this website.
Description: Tolrestat (AY27773) is a novel, potent, orally bioactive aldose reductase inhibitor with IC50 of 35 nM.
References:
1. SestanjK, et al.N-5-(trifluoromethyl)-6-methoxy-1-naphthalenylthioxomethyl-N-methylglycine (Tolrestat), a potent, orally active aldose reductaseinhibitor. J Med Chem. 1984 Mar; 27(3):255-6.
2. Simard-DuquesneN, et al. The effects of a new aldose reductase inhibitor (tolrestat)in galactosemic and diabetic rats. Metabolism. 1985 Oct; 34(10):885-92.
3. SrivastavaS, et al. Aldose reductase protects against early atheroscleroticlesion formation in apolipoprotein E-null mice. Circ Res. 2009 Oct9; 105(8):793-802.
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
Request Data Sheet
Request product datasheet
Request safety datasheet
Compare
Add to wishlist
Recommend by mail
Get an offer
Request delivery time
Ask a technical question
Submit a bulk request
sales@hoelzel.de
« Back
Subscribe, get 15% off every fifth order and have your items delivered on time!
Forgot Your Password?
Not yet registered? Create account here!