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Description: Delavirdine (U-90152; BHAP-U 90152) is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor (NNRTI) of HIV-1 used as part of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) type 1. Although delavirdine was approved by the U.S. Food and Drug Administration in 1997, its efficacy is lower than other NNRTIs, especially efavirenz, and it also has an inconvenient schedule. These factors have led the U.S. DHHS not to recommend its use as part of initial therapy.
References: Antimicrob Agents Chemother. 1993 May; 37(5):1127-31.
Related CAS: 136817-59-9 (free base) 147221-93-0 (mesylate)
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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