JavaScript seems to be disabled in your browser. You must have JavaScript enabled in your browser to utilize the functionality of this website.
Description: Triapine (formerly NSC-663249; AIDS-179996; AP; OCX191; PAN-811; OCX-191; 3AP; NSC663249; PAN811; 3-AP; PAN 811) is a so-called ribonucleotide reductase inhibitor being investigated for cancer treatment. It is also a potent radiosensitizer and a DNA synthesis inhibitor with a broad spectrum antcancer activity. Triapine displays potent anti-proliferative activity in vitro against various cancer cell lines such as murine M109 lung carcinoma and human A2780 ovarian carcinoma. Moreover, Triapine shows high in vivo antitumor efficacy against the M109 lung carcinoma and human A2780 ovarian carcinoma xenograft mice.
References: Biochem Pharmacol. 2000 Apr 15; 59(8):983-91; CNS Drug Rev. 2006 Spring; 12(1):77-90.
Related CAS #: 143621-35-6 or 236392-56-6
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
Request Data Sheet
Request product datasheet
Request safety datasheet
Compare
Add to wishlist
Recommend by mail
Get an offer
Request delivery time
Ask a technical question
Submit a bulk request
sales@hoelzel.de
« Back
Subscribe, get 15% off every fifth order and have your items delivered on time!
Forgot Your Password?
Not yet registered? Create account here!