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sb431542

sb431542

Item no.	V1358-100mg
Manufacturer	InvivoChem LLC
CASRN	301836-41-9
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1358CAS #:301836-41-9Purity >=98% Description: SB431542 (SB-431542; SB 431542) is a novel and selective inhibitor of ALK5/TGF-beta type I Receptor with potential antitumor activity. It inhibits ALK5/TGF-beta with an IC50 of 94 nM in a cell-free assay, and exhibits 100-fold selectivity for ALK5 over p38 MAPK and other kinases. References: J Med Chem. 2002; 45(5):999-1001; Mol Pharmacol. 2002; 62(1):65-74; Oncol Rep. 2010; 24(6):1637-43.
Molecular Weight (MW)	384.39
Formula	C22H16N4O3
CAS No.	301836-41-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 77 mg/mL (200.3 mM)
	Water: < 1 mg/mL
	Ethanol: 3 mg/mL (7.8 mM)
Solubility (In vivo)	2% DMSO+30% PEG 300+ddH2O: 5mg/mL
Synonyms	SB431542; SB-431542; SB 431542

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100mg

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Delivery expected until 9/6/2024