bpdba

Item no.	V13051-500mg
Manufacturer	InvivoChem LLC
CASRN	312281-74-6
Amount	500mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V13051CAS #:312281-74-6Purity >=98% Description: BPDBA is a novel, potent and noncompetitive inhibitor of the betaine/GABA transporter 1 (BGT1) with the potential for treating epilepsy. BGT1 has emerged as an interesting target for treating epilepsy due to animal studies that reported anticonvulsant effects for the GAT1/BGT1 selective inhibitor EF1502 and the BGT1 selective inhibitor RPC-425. References: https://pubmed.ncbi.nlm.nih.gov/31108110/; Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/gamma-Aminobutyric Acid Transporter 1 (BGT1). J Med Chem. 2017 Nov 9; 60(21):8834-8846. doi: 10.1021/acs.jmedchem.7b00924. Epub 2017 Oct 19. PubMed PMID: 28991462.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500mg

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