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Description: Amfebutamone HCl (Bupropion, Wellbutrin, Zyban; BW-323; NSC315851; NSC-315851), the hydrochloride salt of Amfebutamone, is a potent and selective norepinephrine-dopamine reuptake inhibitor used as an antidepressant and for smoking cessation. It inhibits the reuptake of dopamine and norepinephrine with IC50s of 6.5 and 3.4 uM, respectively. Amfebutamone is one of the most frequently prescribed antidepressants in the United States.
References: J Pharmacol Exp Ther. 1999 Jan; 288(1):88-92.
Related CAS #: 31677-93-7 (HCl) 34841-39-9 (free base)
Chemical Name: 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one hydrochloride
InChi Key: HEYVINCGKDONRU-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H18ClNO.ClH/c1-9(15-13(2, 3)4)12(16)10-6-5-7-11(14)8-10; /h5-9, 15H, 1-4H3; 1H
SMILES Code: CC(NC(C)(C)C)C(C1=CC=CC(Cl)=C1)=O.[H]Cl
NSC-315851; Bupropion, Wellbutrin, Zyban; BW 323; NSC315851; NSC 315851; BW-323; BW323.
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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