Comparison

chlorpromazine-hcl

Item no. V1249-25g
Manufacturer InvivoChem LLC
CASRN 69-09-0
Amount 25g
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V1249CAS #:69-09-0Purity >=98%

Description: Chlorpromazine HCl (Promacid; Chloractil; Klorpromex; Fenactil; Largactil; Propaphenin; Sonazine; Thorazine), the Hydrochloride salt form of chlorpromazine, is a potent dopamine and potassium channel inhibitor used as an antipsychotic medication for the treatment of psychotic disorders such as schizophrenia. It inhibits dopamine and potassium channel with IC50s of 6.1 and 16 uM for inward-rectifying K+ currents and time-independent outward currents. Chlorpromazine HCl is a phenothiazine and traditional antipsychotic agent with anti-emetic activity. It exerts antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain.

Description:

References: J Neurosci. 1999 Apr 1; 19(7):2474-88; J Immunol. 1995 Jan 15; 154(2):861-70.

References:

Related CAS #: 69-09-0 (HCl) 50-53-3 (free)

Molecular Weight (MW)
355.33
Formula
C17H19ClN2S.HCl
CAS No.
69-09-0
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 71 mg/mL (199.8 mM)
Water: N/A
Ethanol: 71 mg/mL (199.8 mM)
Other info

Chemical Name: 3-(2-chlorophenothiazin-10-yl)-N, N-dimethylpropan-1-amine; hydrochloride

InChi Key: FBSMERQALIEGJT-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20; /h3-4, 6-9, 12H, 5, 10-11H2, 1-2H3; 1H

SMILES Code: CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl

Synonyms

Promacid; Chloractil; Klorpromex; Fenactil; Hydrochloride, Chlorpromazine; Largactil; Propaphenin; Chloropromazine Hydrochloride; Sonazine; Thorazine

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25g
Available: In stock
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