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Description: Desloratadine (formerly SCH34117, NSC 675447; SCH-34117, NSC-675447; Clarinex; Neoclarityn; Descarboethoxyloratadine; Aerius) is the active metabolite of loratadine which is an anti-histamine drug of the tricyclic class used to treat allergies. Desloratadine is a potent antagonist for human histamine H1 receptor with an IC50 of 51 nM.
References: Eur J Pharmacol. 1999 Jun 18; 374(2):249-54; J Allergy Clin Immunol. 2001 Apr; 107(4):751-62.
Related CAS#: 79794-75-5 (Loratadine); 165739-83-3 (4-Chloroloratadine); 170727-59-0 (Isoloratadine); 125743-80-8 (Loratadine impurity F)
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