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desloratadine

desloratadine

Item no.	V1242-250mg
Manufacturer	InvivoChem LLC
CASRN	100643-71-8
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1242CAS #:100643-71-8 Purity >=98% Description: Desloratadine (formerly SCH34117, NSC 675447; SCH-34117, NSC-675447; Clarinex; Neoclarityn; Descarboethoxyloratadine; Aerius) is the active metabolite of loratadine which is an anti-histamine drug of the tricyclic class used to treat allergies. Desloratadine is a potent antagonist for human histamine H1 receptor with an IC50 of 51 nM. Description: References: Eur J Pharmacol. 1999 Jun 18; 374(2):249-54; J Allergy Clin Immunol. 2001 Apr; 107(4):751-62. References: Related CAS#: 79794-75-5 (Loratadine); 165739-83-3 (4-Chloroloratadine); 170727-59-0 (Isoloratadine); 125743-80-8 (Loratadine impurity F)
Molecular Weight (MW)	310.82
Formula	C19H19ClN2
CAS No.	100643-71-8 (Desloratadine);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 26 mg/mL (83.6 mM)
	Water: < 1 mg/mL
	Ethanol: 62 mg/mL (199.5 mM)
Solubility (In vivo)	30% Propylene glycol, 5% Tween 80, 65% D5W: 30 mg/mL
Synonyms	SCH34117, NSC675447; SCH 34117, NSC 675447; SCH-34117, NSC-675447; Desloratadine; Clarinex; Neoclarityn; Descarboethoxyloratadine; Aerius

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Amount: 250mg

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