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mizolastine

mizolastine

Item no.	V1234-50mg
Manufacturer	InvivoChem LLC
CASRN	108612-45-9
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	108612-45-9
Available
Description	InvivoChem Cat #:V1234CAS #:108612-45-9Purity >=98% Description: Mizolastine (Mizollen; SL 85.0324; Mistalin; SL-850324; SL 850324; Mistamine; Mizolastina) is a histamine H1-receptor antagonist with anti-allergic effects. It inhibits histamine H1-receptor with an IC50 of 47 nM and has been used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. Mizolastine is a once-daily, non-sedating antihistamine. It blocks H1 receptors and is commonly fast-acting. It does not prevent the actual release of histamine from mast cells, just prevents it binding to receptors. Side effects can include dry mouth and throat. Description: References: BioDrugs. 1998 Jul; 10(1):41-63.; Wikipedia References:
Molecular Weight (MW)	432.49
Formula	C24H25FN6O
CAS No.	108612-45-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: < 1 mg/mL
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	Chemical Name: 2-((1-(1-(p-Fluorobenzyl)-2-benzimidazolyl)-4-piperidyl)methylamino)-4(3H)-pyrimidinone InChi Key: PVLJETXTTWAYEW-UHFFFAOYSA-N InChi Code: InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10, 13, 19H, 11-12, 14-16H2, 1H3, (H, 26, 28, 32) SMILES Code: O=C1NC(N(C2CCN(C3=NC4=CC=CC=C4N3CC5=CC=C(F)C=C5)CC2)C)=NC=C1
Synonyms	SL-850324; Mizollen; SL 85.0324; Mistalin; SL850324; SL 850324; Mistamine; Mizolastina; Mizolastine

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