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buclizine-hcl

buclizine-hcl

Item no.	V1226-100mg
Manufacturer	InvivoChem LLC
CASRN	129-74-8
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #: V1226CAS #:129-74-8Purity >=98% Description: Buclizine hydrochloride (AH-2526, UCB 4445; AH2526; UCB-4445, Buclina, Longifene, Posdel, Vibazine), the hydrochloride salt of buclizine which is used for motion sickness, is a piperazine derivative and a sedating antihistamine with antimuscarinic and moderate sedative action. Buclizine has been used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Description: References: Profiles Drug Subst Excip Relat Methodol. 2011; 36:1-33. References: Related CAS #: 129-74-8 (HCl) 82-95-1 (free base).
Molecular Weight (MW)	505.95
Formula	C28H33ClN2.2HCl
CAS No.	129-74-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: < 1 mg/mL
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	Chemical Name: 1-(4-(tert-butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride InChi Key: SDBHDSZKNVDKNU-UHFFFAOYSA-N InChi Code: InChI=1S/C28H33ClN2.2ClH/c1-28(2, 3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24; ; /h4-16, 27H, 17-21H2, 1-3H3; 2*1H SMILES Code: ClC1=CC=C(C(N2CCN(CC3=CC=C(C(C)(C)C)C=C3)CC2)C4=CC=CC=C4)C=C1.[H]Cl.[H]Cl
Synonyms	UCB-4445; AH 2526, UCB4445; AH-2526, UCB 4445; AH2526; Buclizine; Buclizine dihydrochloride; AH-2526, UCB 4445; AH2526; UCB-4445, Buclina, Longifene, Posdel, Vibazine.

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Amount: 100mg

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