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Description: Galanthamine HBr (Razadyne, Reminyl), the hydrobromide salt of Galanthamine, is a centrally active and long-acting AChE/acetylcholinesterase inhibitor approved for the treatment of cognitive decline in Alzheimer's disease and various other memory impairments. It inhibits AChE with an IC50 of 0.35 uM, and shows > 50-fold selectivity over butyryl-cholinesterase.
References: Eur J Clin Chem Clin Biochem. 1991 Aug; 29(8):487-92; J Pharmacol Exp Ther. 2007 Aug; 322(2):591-9.
Related CAS No.: 134332-50-6 (Galanthamine N-Oxide)
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