« Back
Home /
5-hydroxymethyl-tolterodine-pnu-200577

5-hydroxymethyl-tolterodine-pnu-200577

Item no.	V1168-2mg
Manufacturer	InvivoChem LLC
CASRN	207679-81-0
Amount	2mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	207679-81-0
Available
Description	InvivoChem Cat #:V1168CAS #:207679-81-0 Purity >=98% Description: 5-hydroxymethyl tolterodine (Desfesoterodine, PNU 200577, PNU-200577, 5HMT, 5HM; 5-HMT, 5-HM), the active metabolite of tolterodine which is a medication used treat overactive bladder, is a novel and potent muscarinic receptor antagonist with a Kb of 0.84 nM. It is a major and pharmacologically active metabolite of tolterodine which used to treat frequent urination, urinary incontinence, or urinary urgency. . 5-hydroxymethyl tolterodine produces a competitive and concentration-dependent inhibition of carbachol-induced contraction of guinea-pig isolated urinary bladder strips. 5-hydroxymethyl tolterodine antagotizes muscarinic receptors with a pA2 of 9.1. Description: References: Pharmacol Toxicol. 1997 Oct; 81(4):169-72. References: Related CAS #: 380636-50-0 (fumarate) 207679-81-0 (free base)
Molecular Weight (MW)	341.49
Formula	C22H31NO2
CAS No.	207679-81-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 68 mg/mL (199.1 mM)
	Water: < 1 mg/mL
	Ethanol: 68 mg/mL (199.1 mM)
Other info	Chemical Name: (R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol InChi Key: DUXZAXCGJSBGDW-HXUWFJFHSA-N InChi Code: InChI=1S/C22H31NO2/c1-16(2)23(17(3)4)13-12-20(19-8-6-5-7-9-19)21-14-18(15-24)10-11-22(21)25/h5-11, 14, 16-17, 20, 24-25H, 12-13, 15H2, 1-4H3/t20-/m1/s1 SMILES Code: OC1=CC=C(CO)C=C1[CH](C2=CC=CC=C2)CCN(C(C)C)C(C)C
Synonyms	Desfesoterodine, PNU-200577; 5-HMT, 5-HM; PNU200577; PNU 200577

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 2mg

available

Delivery expected until 9/6/2024

Express Delivery: Save 7 days

Compare

Add to wishlist

Recommend by mail