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Description: Aripiprazolemonohydrate (also known as OPC-14597) is a novel atypical antipsychotic drug thatis reported to be a high-affinity 5-HT receptor partial agonist. It is adopamine-serotonin system stabilizer with potent partial agonistactivity at dopamine D2 and 5-HT1A receptors and antagonist activity at5-HT2A receptors. In addition, aripiprazole has been reported to labelwith the agonist 125I7-OH-PIPAT and with the antagonist 3Hspiperonewith 0.34+/-0.02nM and 0.70+/-0.22nM, respectively.
References: J Pharmacol Exp Ther. 2002 Jul; 302(1):381-9; Biochem Biophys Res Commun. 1999 Dec 20; 266(2):560-3.
Related CAS #: 129722-25-4Dehydroaripiprazole (OPC-14857; DM-14857); 1089115-06-9 (AripiprazoleD8); 1259305-26-4 (Aripiprazole cavoxil); 1259305-29-7 (Aripiprazolelauroxil); 851220-85-4 (Aripiprazole monohydrate)
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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