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vu-0357121

vu-0357121

Item no.	V1090-25mg
Manufacturer	InvivoChem LLC
CASRN	433967-28-3
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1090CAS #:433967-28-3Purity >=98% Description: VU0357121 (VU-0357121, VU 0357121) is a positive allosteric modulator (PAM) of mGlu5 (metabotropic glutamate receptor 4) with antiparkinsonian-like effects. In inhibits mGlu5 with an EC50 of 33 nM, and exhibits little activity against other mGlu receptor subtypes. Description: References: ACS Chem Neurosci. 2010 Oct 20; 1(10):702-716; Mol Pharmacol. 2012 Nov; 82(5):860-75. References:
Molecular Weight (MW)	305.32
Formula	C17H17F2NO2
CAS No.	433967-28-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 61 mg/mL (199.8 mM)
	Water: < 1 mg/mL
	Ethanol: 21 mg/mL (68.8 mM)
SMILES Code	O=C(NC1=CC=C(F)C=C1F)C2=CC=C(OCCCC)C=C2
Synonyms	VU-0357121, VU0357121, VU 0357121

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 9/6/2024

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