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duloxetine-hcl-ly-248686-hcl

duloxetine-hcl-ly-248686-hcl

Item no.	V1016-100mg
Manufacturer	InvivoChem LLC
CASRN	136434-34-9
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1016CAS #:136434-34-9 Purity >=98% Description: Duloxetine HCl (formerly LY-248686 HCl; LY248686; trade names Cymbalta; Yentreve), the hydrochloride salt of Duloxetine which is an approved antidepressant medication, is a potent serotonin-norepinephrine reuptake inhibitor (SNRI) with potential anti-depressive activity. It inhibits SNRI with a Ki of 4.6 nM. Duloxetine has been used for treating various indications such as major depressive disorders, generalized anxiety disorder (GAD), fibromyalgia and neuropathic pain as well as stress urinary incontinence. Duloxetine is marketed under the brand name Cymbalta among others. Description: References: Life Sci. 1988; 43(24):2049-57. References: Related CAS#: 116539-59-4 (Free base); 949095-98-1 (Para-Naphthol duloxetine, a Duloxetine metabolite); 1435727-97-1 (Duloxetine D3 HCl); 916135-70-1 (N-Methyl Duloxetine)
Molecular Weight (MW)	333.88
Formula	C18H19NOS.HCl
CAS No.	136434-34-9 (HCl)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 67 mg/mL (200.7 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	2% DMSO+30% PEG 300+ddH2O: 30 mg/mL
Synonyms	LY-227942; LY248686; LY-248686 HCl; Duloxetine; LY-248686; LY227942; Cymbalta; (S)-Duloxetine; Yentreve; Duloxetine HCl; duloxetine hydrochloride; duloxetine, (+)-isomer; HCl, LY 227942; LY 248686

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Amount: 100mg

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