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vilazodone-hcl-emd-68843-sb659746a

vilazodone-hcl-emd-68843-sb659746a

Item no.	V0972-1g
Manufacturer	InvivoChem LLC
CASRN	163521-08-2
Amount	1g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0972CAS #:163521-08-2Purity >=98% Description: Vilazodone HCl (SB659746A; SB659746-A; EMD-68843; EMD68843; Viibryd), the hydrochloride salt of Vilazodone, is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of 5-HT1A receptors with anti-depressive effects. As of 2011, Vilazodone was approved by the FDA to treat major depressive disorders. Vilazodone demonstrates an IC50 of 0.2 nM at the human 5-HT1A receptor and 0.5 nM for the SERT. Vilazodone displays high affinity (pKi >= 9.3) for human recombinant and rat, guinea pig, mouse, and marmoset native tissue 5-HT1A receptors. Description: References: CNS Neurosci Ther. 2009 Summer; 15(2):107-17; Eur J Pharmacol. 2005 Mar 7; 510(1-2):49-57. References: Related CAS: 163521-12-8 (free base); 1794789-93-7 (Vilazodone D8); 163521-19-5 (Vilazodone carboxylic acid)
Molecular Weight (MW)	477.99
Formula	C26H27N5O2.HCl
CAS No.	163521-08-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 96 mg/mL (200.8 mM)
	Water: < 1 mg/mL
	Ethanol:< 1 mg/mL
SMILES Code	O=C(C1=CC2=CC(N3CCN(CCCCC4=CNC5=C4C=C(C#N)C=C5)CC3)=CC=C2O1)N.[H]Cl
Synonyms	EMD68843; SB659746A; SB659746-A; EMD-68843; EMD68843; SB659746 A; Vilazodone hydrochloride; Viibryd

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