« Back
Home /
torcetrapib

torcetrapib

Item no.	V0912-5mg
Manufacturer	InvivoChem LLC
CASRN	262352-17-0
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	262352-17-0
Available
Description	InvivoChem Cat #:V0912CAS #:262352-17-0Purity >=98% Description: Torcetrapib (formerly CP 529414; CP-529, 414; CP-529414) is a novel and potent CETP (Cholesteryl ester transfer protein) inhibitor with the potential to lower cholesterol levels and to treat cardiovascular diseases. It inhibits CETP with an IC50 of 37 nM. Torcetrapib is able to elevate plasma HDL-C and reducs non-HDL-C, and thus is being studied to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease. Description: References: Endocrinology. 2009 May; 150(5):2211-9; Arterioscler Thromb Vasc Biol. 2004 Mar; 24(3):490-7. References:
Molecular Weight (MW)	600.47
Formula	C26H25F9N2O4
CAS No.	262352-17-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 120 mg/mL (199.8 mM)
	Water: < 1 mg/mL
	Ethanol: 6 mg/mL (10.0 mM)
Other info	Chemical Name: ethyl (2R, 4S)-4-[[3, 5-bis(trifluoromethyl)phenyl]methyl-methoxycarbonylamino]-2-ethyl-6-(trifluoromethyl)-3, 4-dihydro-2H-quinoline-1-carboxylate InChi Key: CMSGWTNRGKRWGS-NQIIRXRSSA-N InChi Code: InChI=1S/C26H25F9N2O4/c1-4-18-12-21(19-11-15(24(27, 28)29)6-7-20(19)37(18)23(39)41-5-2)36(22(38)40-3)13-14-8-16(25(30, 31)32)10-17(9-14)26(33, 34)35/h6-11, 18, 21H, 4-5, 12-13H2, 1-3H3/t18-, 21+/m1/s1 SMILES Code: O=C(N1[CH](CC)C[CH](N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C(OC)=O)C3=C1C=CC(C(F)(F)F)=C3)OCC
Synonyms	CP529, 414; CP-529414; CP529414; Torcetrapib; CP 529414; CP-529, 414; CP 529, 414;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5mg

available

Delivery expected until 9/6/2024

Express Delivery: Save 15 days

Compare

Add to wishlist

Recommend by mail