u-104

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	500mg
Item no.	V0895-500mg
CASRN	178606-66-1
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V0895CAS #:178606-66-1Purity >=98% Description: U-104 (MST-104; U104; SLC-0111; NSC-213841) is a novel and potent inhibitor of transmembrane carbonic anhydrase (CA) with potential antineoplastic activity. It inhibits CA IX and CA XII with Ki values of 45.1 nM and 4.5 nM respectively. U-104 shows high in vivo antitumor efficacy in Balb/c mice orthotopically implanted with 4T1 cells. Description:Balb/c mice orthotopically implanted with 4T1 cells. References: Cancer Res. 2011 May 1; 71(9):3364-76; Oncogene. 2013 Oct 31; 32(44):5210-9. References:
Molecular Weight (MW)	309.32
Formula	C13H12FN3O3S
CAS No.	178606-66-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 62 mg/mL (200.4 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	30% PEG400+0.5% Tween80+5% propylene glycol: 30 mg/mL
Synonyms	MST-104, SLC0111; SLC 0111; U-104; NSC 213841; MST104; MST 104; NSC-213841; NSC213841; SLC-0111; U104; U 104.

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