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Description: Ammonium Glycyrrhizinate (AMGZ, Glycyram; Monoammonium glycyrrhizinate), a triterpenoid saponin analog, is responsible for the sweet-tasting of Glycyrrhiza glabra root. It acts as a direct HMGB1 antagonist and can potently inhibit growth and cytopathology of several unrelated DNA and RNA viruses. It is cytoprotective agent. Ammonium Glycyrrhizinate is able to inhibit the production of ROS. It has antioxidant activity and is effective for the treatment of gastric diseases related to the oxidative stress-induced mucosal damage.
References: Exp Biol Med. 2009; 234(3):263-77; Eksp Klin Farmakol. 1997; 60(2):65-7; Int J Nanomedicine. 2014; 9:635-51.
Related CAS #: 1405-86-3 (Glycyrrhizic acid)
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