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agi-6780

agi-6780

Item no.	V0862-10mg
Manufacturer	InvivoChem LLC
CASRN	1432660-47-3
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1432660-47-3
Available
Description	InvivoChem Cat #:V0862CAS #:1432660-47-3Purity >=98% Description: AGI-6780 (AGI6780; AGI 6780) is a potent and selective inhibitor of tumor-associated mutant IDH2 (isocitrate dehydrogenases 2) R140Q with potential anti-inflammatory activity. It inhibits IDH2 R140Q with an IC50 of 23 nM. It shows less potency against IDH2(WT) with an IC50 of 190+/-8.1 nM. Description: References: Science. 2013 May 3; 340(6132):622-6. References:
Molecular Weight (MW)	481.51
Formula	C21H18F3N3O3S2
CAS No.	1432660-47-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 96 mg/mL (199.4 mM)
	Water: < 1 mg/mL
	Ethanol: 96 mg/mL (199.4 mM)
SMILES	O=S(C1=CC=C(C2=CSC=C2)C(NC(NC3=CC=CC(C(F)(F)F)=C3)=O)=C1)(NC4CC4)=O
Synonyms	AGI 6780; AGI-6780; ; AGI6780; N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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