u73122

Item no.	V0845-5mg
Manufacturer	InvivoChem LLC
CASRN	112648-68-7
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	112648-68-7
Available
Description	InvivoChem Cat #:V0845CAS #:112648-68-7Purity >=98% Description: U73122 (U 73122; U-73122) is a novel and potent phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with potential anti-inflammatory activity. It inhibits PLC with an IC50 of 1-2.1 uM. U73122 can also acts as an inhibitor of myocardial PLD by interaction with PIP2 as a cofactor for optimal PLD activity. Description: References: J Pharmacol Exp Ther. 1990 Nov; 255(2):756-68; J Pharmacol Exp Ther. 2004 May; 309(2):697-704. References:
Molecular Weight (MW)	464.64
Formula	C29H40N2O3
CAS No.	112648-68-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 0.01 mg/mL warmed (0.02 mM)
	Water: < 1 mg/mL
	Ethanol:N/A
Solubility (In vivo)	2% Tween 80+saline: 5mg/mL
Synonyms	U 73122; U73122; U73122. Chemical Name: 1-(6-(((8R, 9S, 13S, 14S, 17S)-3-methoxy-13-methyl-7, 8, 9, 11, 12, 13, 14, 15, 16, 17-decahydro-6H-cyclopenta[a]phenanthren-17-yl)amino)hexyl)-1H-pyrrole-2, 5-dione InChi Key: LUFAORPFSVMJIW-ZRJUGLEFSA-N InChi Code: InChI=1S/C29H40N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8, 10, 13-14, 19, 23-26, 30H, 3-7, 9, 11-12, 15-18H2, 1-2H3/t23-, 24-, 25+, 26+, 29+/m1/s1 SMILES Code: O=C(C=C1)N(CCCCCCN[CH]2CC[C]3([H])[C]4([H])CCC5=CC(OC)=CC=C5[C]4([H])CC[C]23C)C1=O

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5mg

available

Delivery expected until 9/6/2024

Express Delivery: Save 18 days

Compare

Add to wishlist

Recommend by mail