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ciprofibrate

ciprofibrate

Item no.	V0833-2g
Manufacturer	InvivoChem LLC
CASRN	52214-84-3
Amount	2g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0833CAS #:52214-84-3Purity >=98% Description: Ciprofibrate (BRN-1984981; CCRIS 173; CCRIS173; Win-35833; BRN 1984981; BRN1984981; CCRIS-173) is a potent and selective agonist of PPAR/peroxisome proliferator-activated receptor agonist with antilipidemic activity. It was developed and approved in 1985 as a lipid-lowering agent. Ciprofibrate acts by activating PPARalpha with an EC50 value of 20 uM and only marginally affects PPARgamma (EC50 = > 300 uM). It has been shown to lower adipose tissue weight and reduce plasma insulin concentrations in obese rats and has been used clinically in the treatment of dyslipidemia. Description: References: J Biol Chem. 2000 Jun 2; 275(22):16638-42. References:
Molecular Weight (MW)	289.15
Formula	C13H14Cl2O3
CAS No.	52214-84-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 58 mg/mL (200.6 mM)
	Water: < 1 mg/mL
	Ethanol: 58 mg/mL (200.6 mM)
Other info	Chemical Name: 2-(4-(2, 2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid InChi Key: KPSRODZRAIWAKH-UHFFFAOYSA-N InChi Code: InChI=1S/C13H14Cl2O3/c1-12(2, 11(16)17)18-9-5-3-8(4-6-9)10-7-13(10, 14)15/h3-6, 10H, 7H2, 1-2H3, (H, 16, 17) SMILES Code: CC(C)(OC1=CC=C(C2C(Cl)(Cl)C2)C=C1)C(O)=O
Synonyms	BRN-1984981; CCRIS 173; CCRIS173; Win-35833; BRN 1984981; BRN1984981; CCRIS-173; Ciprofibrate; WIN 35833; WIN35833

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