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avanafil

avanafil

Item no.	V0797-500mg
Manufacturer	InvivoChem LLC
CASRN	330784-47-9
Amount	500mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0797CAS #:330784-47-9Purity >=98% Description: Avanafil (also known as TA 1790; TA1790; TA-1790; trade name: Stendra; Spedra) is a highly potent and selective PDE5 inhibitor with potential vasodilating effects. It inhibits PDE5 with an IC50 of 5.2 nM, and shows > 121-fold selectivity for PDE5 over other isoforms of PDE. As of 2012, Avanafil was approved by the US FDA for the treatment of erectile dysfunction. Description: References: J Urol. 2012 Aug; 188(2):668-74; Urology. 2014 Feb; 83(2):508.e7-12. References:
Molecular Weight (MW)	483.95
Formula	C23H26ClN7O3
CAS No.	330784-47-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 97 mg/mL (200.4 mM)
	Water:< 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: (S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2pyrimidinylmethyl)-5-pyrimidinecarboxamide InChi Key: WEAJZXNPAWBCOA-INIZCTEOSA-N InChi Code: InChI=1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3, 5-8, 10, 12, 16, 32H, 2, 4, 9, 11, 13-14H2, 1H3, (H, 28, 33)(H, 27, 29, 30)/t16-/m0/s1 SMILES Code: O=C(C1=CN=C(N2[CH](CO)CCC2)N=C1NCC3=CC=C(OC)C(Cl)=C3)NCC4=NC=CC=N4
Synonyms	TA 1790; TA1790; Avanafil; TA-1790; trade name: Stendra; Spedra

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Amount: 500mg

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Delivery expected until 9/6/2024