Comparison

andrographolide

Item no. V0768-10g
Manufacturer InvivoChem LLC
CASRN 5508-58-7
Amount 10g
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V0768CAS #:5508-58-7Purity >=98%

Description: Andrographolide, a naturally occuring labdane diterpenoid extracted from the stem and leaves of Andrographis paniculata, is an irreversible/covalent NF-kappaB inhibitor with potential anti-inflammatory activity. It inhibits NF-kappaB activation by forming a covalent bond with the cysteine residue on p50 in endothelial cells.

References: J Immunol. 2004 Sep 15; 173(6):4207-17.

Molecular Weight (MW)
350.45
Formula
C20H30O5
CAS No.
5508-58-7
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 70 mg/mL (199.7 mM)
Water: < 1 mg/mL
Ethanol: < 1 mg/mL
Other info

InChi Key: BOJKULTULYSRAS-WLRTZDKTSA-N

InChi Code: InChI=1S/C20H30O5/c1-12-4-7-16-19(2, 9-8-17(23)20(16, 3)11-21)14(12)6-5-13-15(22)10-25-18(13)24/h5, 14-17, 21-23H, 1, 4, 6-11H2, 2-3H3/b13-5+

SMILES Code: O=C1OCC(O)/C1=C\CC2C(CCC3C(C)(CO)C(O)CCC23C)=C

Synonyms
Andrographis; Chemical Name: 3-[2-[decahydro-6-hydroxy-5- (hydroxymethyl)-5, 8a- dimethyl-2-methylene-1- napthalenyl]ethylidene]dihydro- 4-hydroxy-2(3H)-furanone

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10g
Available: In stock
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