vx-702

Item no.	V0480-250mg
Manufacturer	InvivoChem LLC
CASRN	745833-23-2
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0480CAS #:745833-23-2 Purity >=98% Description: VX-702 is a novel, highly potent, orally bioavailable and selective inhibitor of p38alpha MAPK with potential anti-inflammatory activity. It inhibits p38alpha MAPK with 14-fold higher potency than p38beta. It is one of the 2nd-generation and orally bioactive p38 MAP kinase inhibitors that are potentially useful for the treatment of inflammation, rheumatoid arthritis and cardiovascular diseases. VX-702 prevents activation of p38MAPK and decrements in many platelet storage parameters after exposure to 16 C without agitation for 24 h. Description: References: Thromb Haemost. 2004 Dec; 92(6):1387-93; Circulation. 2003; 108:e9045-e9046. References: Related CAS: 479543-46-9
Molecular Weight (MW)	404.3
Formula	C19H12F4N4O2
CAS No.	745833-23-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 81 mg/mL (200.3 mM)
	Water: < 1 mg/mL
	Ethanol:< 1 mg/mL
Solubility (In vivo)	30% PEG400+0.5% Tween80+5% propylene glycol: 30mg/mL
Synonyms	VX-702; VX 702; VX702

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250mg

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