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Description: BRD4770 (BRD-4770) is a novel and selective inhibitor of G9a (a histone methyltransferase, also known as euchromatin histone methyltransferase 2 (EHMT2)) with anticancer activity. It inhibits G9a with an IC50 of 6.3 uM, and can induce cell senescence. It exhibits excellent antiproliferative activity against various cancer cell lines such as pancreatic cancer cells-PANC-1.
References: ACS Chem Biol. 2012 Jul 20; 7(7):1152-7; Cell Death Dis. 2013 Jun 27; 4:e690.
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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