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cct129202

cct129202

Item no.	V0359-25mg
Manufacturer	InvivoChem LLC
CASRN	942947-93-5
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0359CAS #:942947-93-5Purity >=98% Description: CCT129202 (CCT-129202), an imidazopyridine compound, is a potent and ATP-competitive pan-Aurora inhibitor with potential antitumor activity. It inhibits Aurora A, Aurora B and Aurora C with IC50s of 0.042 uM, 0.198 uM and 0.227 uM, respectively. CCT129202 shows potent in vitro antiproliferative activity and high in vivo antitumor efficacy. Description: References: Mol Cancer Ther. 2007 Dec; 6(12 Pt 1):3147-57. References:
Molecular Weight (MW)	497.02
Formula	C23H25ClN8OS
CAS No.	942947-93-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 3 mg/mL (6.0 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	1% DMSO+30% polyethylene glycol+1% Tween 80: 30 mg/mL
Synonyms	Synonym: CCT-129202; CCT 129202; CCT129202. Chemical Name: 2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imidazo[4, 5-b]pyridin-7-yl)piperazin-1-yl)-N-(thiazol-2-yl)acetamide InChi Key: QYKHWEFPFAGNEV-UHFFFAOYSA-N InChi Code: InChI=1S/C23H25ClN8OS/c1-30(2)16-5-3-15(4-6-16)21-28-19-20(17(24)13-26-22(19)29-21)32-10-8-31(9-11-32)14-18(33)27-23-25-7-12-34-23/h3-7, 12-13H, 8-11, 14H2, 1-2H3, (H, 25, 27, 33)(H, 26, 28, 29) SMILES Code: O=C(NC1=NC=CS1)CN2CCN(C3=C4C(NC(C5=CC=C(N(C)C)C=C5)=N4)=NC=C3Cl)CC2

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Amount: 25mg

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Delivery expected until 10/4/2024

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