Comparison

sodiumphenylbutyrate

Item no. V0284-2g
Manufacturer InvivoChem LLC
CASRN 1716-12-7
Amount 2g
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V0284CAS #:1716-12-7Purity >=98%

Description: Sodium phenylbutyrate (4-Phenylbutyric acid sodium; 4-PBA sodium), an orphan drug marketed by Ucyclyd Pharma, is a novel and potent histone deacetylase (HDAC) inhibitor used as an as adjunctive therapy for chronic treatment of urea cycle disorders involving deficiencies of argininosuccinic acid synthetase (AS), ornithine transcarbamylase (OTC), or carbamylphosphate synthetase (CPS). As the metabolites of Sodium phenylbutyrate offer an alternative pathway to the urea cycle to allow excretion of excess nitrogen. It also has potent anti-cancer activity.

Description:

References: Neuromolecular Med. 2004; 5(3):235-41; J Neurochem. 2005; 93(5):1087-98; J Biol Chem. 2005; 280(1):556-63.

References:
Molecular Weight (MW)
186.18
Formula
C10H11O2.Na
CAS No.
1716-12-7
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 30 mg/mL (161.1 mM)
Water: < 1 mg/mL
Ethanol: 8 mg/mL (43.0 mM)
Solubility (In vivo)

Chemical Name: sodium 4-phenylbutanoate

InChi Key: VPZRWNZGLKXFOE-UHFFFAOYSA-M

InChi Code: InChI=1S/C10H12O2.Na/c11-10(12)8-4-7-9-5-2-1-3-6-9; /h1-3, 5-6H, 4, 7-8H2, (H, 11, 12); /q; +1/p-1

SMILES Code: O=C([O-])CCCC1=CC=CC=C1.[Na+]

Synonyms

4-PBA sodium; Sodium 4-phenylbutyrate; Sodium phenylbutyrate; 4-phenylbutyrate (4-PBA); 4-phenylbutyric acid; Buphenyl

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 2g
Available: In stock
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