m344

Item no.	V0278-250mg
Manufacturer	InvivoChem LLC
CASRN	251456-60-7
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0278CAS #:251456-60-7Purity >=98% Description: M344 (D-237; MS-344), an amide analogue of Trichostatin A, is a novel and potent pan-HDAC (histone deacetylase) inhibitor with potential anticancer activity. In inhibits HDAC with an IC50 of 100 nM and shows potent anti-proliferative activity in vitro against various cancer cell lines such as MCF-7 cells. It can also induce cell differentiation. Description: References: J Med Chem. 1999 Nov 4; 42(22):4669-79; Gynecol Oncol. 2006 Apr; 101(1):108-13; Int J Cancer. 2007 Apr 15; 120(8):1787-94; Cancer Cell Int. 2010 Sep 9; 10:32. References:
Molecular Weight (MW)	307.39
Formula	C16H25N3O3
CAS No.	251456-60-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 62 mg/mL (201.7 mM)
	Water: < 1 mg/mL
	Ethanol: 4 mg/mL (13.0 mM)
SMILES	O=C(NCCCCCCC(NO)=O)C1=CC=C(N(C)C)C=C1
Synonyms	M344; D 237; MS 344; M-344; D-237; MS-344; M-344; D237; MS344

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