« Back
Home /
bi-d1870

bi-d1870

Item no.	V0238-5mg
Manufacturer	InvivoChem LLC
CASRN	501437-28-1
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	501437-28-1
Available
Description	InvivoChem Cat #:V0238CAS #:501437-28-1Purity >=98% Description: BI-D1870 is a specific, cell permeable and ATP-competitive inhibitor of RSK1/2/3/4 (p90 ribosomal S6 kinase) with the potential to treat autoimmune encephalomyelitis (EAE). It inhibits RSK1/2/3/4 with IC50s of 31 nM/24 nM/18 nM/15 nM in cell-free assays, respectively. and displays 10- to 100-fold higher selectivity for RSK over MST2, GSK-3beta, MARK3, CK1 and Aurora B. RSKs are serine/threonine kinases that are involved in various cellular processes including growth, survival, and motility. BI-D1870 also showed potent antiproliferative activity in vitro. Description: Description: BI-D1870 is a specific, cell permeable and ATP-competitive inhibitor of RSK1/2/3/4 (p90 ribosomal S6 kinase) with the potential to treat autoimmune encephalomyelitis (EAE). It inhibits RSK1/2/3/4 with IC50s of 31 nM/24 nM/18 nM/15 nM in cell-free assays, respectively. and displays 10- to 100-fold higher selectivity for RSK over MST2, GSK-3beta, MARK3, CK1 and Aurora B. RSKs are serine/threonine kinases that are involved in various cellular processes including growth, survival, and motility. BI-D1870 also showed potent antiproliferative activity in vitro.BI-D1870 References: Biochem J. 2007 Jan 1; 401(Pt 1): 29–38. References:References:

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5mg

available

Delivery expected until 9/6/2024

Express Delivery: Save 21 days

Compare

Add to wishlist

Recommend by mail