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indirubin

indirubin

Item no.	V0225-25mg
Manufacturer	InvivoChem LLC
CASRN	479-41-4
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0225CAS #:479-41-4Purity >=98% Description: Indirubin (also known as NSC-105327; Couroupitine B) is a potent and selective inhibitor of CDK (cyclin-dependent kinases) and GSK-3beta (glycogen synthase kinase-3) with potential antitumor activity. It inhibits CDK and GSK-3beta with IC50s of ca.5 uM and 0.6 uM, respectively. Indirubin is a nturally occuring and the active ingredient of Danggui Longhui Wan, a mixture of traditional Chinese herbal medicine. Description:Description: Indirubi is a potent and selective inhibitor of CDK (cyclin-dependent kinases) and GSK-3beta (glycogen synthase kinase-3) with potential antitumor activity. It inhibits CDK and GSK-3beta with IC50s of ca.5 uM and 0.6 uM, respectively. Indirubin is a nturally occuring and the active ingredient of Danggui Longhui Wan, a mixture of traditional Chinese herbal medicine. GSK-3beta References: J Biol Chem. 2006 Aug 18; 281(33):23425-35; J Biol Chem. 2001 Jan 5; 276(1):251-60. References: References:

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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