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Description: MQAE (N-ethoxycarbonylmethyl-6-methoxy-quinolinium bromide) is an analog of 6-methoxyquinolinium. It is a novel fluorescent indicator/dye for detection of intracellular Cl-. MQAE detects the ion when quenched via collision with chloride. It is more frequently used for chloride measurement as it is more sensitive and selective than 36Cl and microelectrode-based methods. MQAE is a useful fluorescence dye for noninvasive measurements of the intracellular Cl-.
References: Am J Physiol. 1994 Dec; 267(6 Pt 2):H2114-23; Cold Spring Harb Protoc. 2012 Jul 1; 2012(7):778-85.
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