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doxapram

doxapram

Item no.	V0087-500mg
Manufacturer	InvivoChem LLC
CASRN	309-29-5
Amount	500mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0087CAS #:309-29-5Purity >=98% Description: Doxapram (AHR619, Dopram, Stimulex or Respiram) is a novel potent respiratory stimulant that acts by inhibiting the potassium channels such as TASK-1, TASK-3, TASK-1/TASK-3 with EC50 of 410 nM, 37 uM, 9 uM, respectively. It is a medication used in intensive care settings to stimulate the respiratory rate in patients with respiratory failure. References: Anesth Analg. 2006 Mar; 102(3):779-85. Related CAS: 7081-53-0 (HCl) 309-29-5 (free base)
Molecular Weight (MW)	378.51
Formula	C24H30N2O2
CAS No.	309-29-5 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 10 mM
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Chemical Name	1-ethyl-4- (2-morpholin-4-ylethyl)- 3, 3-diphenyl-pyrrolidin-2-one
Synonyms	AHR619; AHR-619; AHR 619; Dopram, Stimulex or Respiram.
SMILES Code	O=C1N(CC)CC(CCN2CCOCC2)C1(C3=CC=CC=C3)C4=CC=CC=C4

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Amount: 500mg

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