« Back
Home /
unc-926

unc-926

Item no.	V0086-50mg
Manufacturer	InvivoChem LLC
CASRN	1184136-10-4
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0086CAS #:1184136-10-4 Purity >=98% Description: UNC-926 is a potent and selective inhibitor of the L3MBTL1 (Lethal(3)malignant brain tumor-like protein) domain (Kd = 3.9 uM), which is a methyl-lysine (Kme) reader domain. UNC-926 acts by binding to the MBT domain of the L3MBTL1 protein. In a peptide pull down assay, UNC-926 was found to be able to selectively inhibits the L3MBTL1_3XMBT-H4K20me1 interaction. References: Med. Chem. Commun., 2012, 3, 45-51; Bioorg Med Chem Lett. 2016 Sep 15; 26(18):4436-4440. Related CAS: 1782573-49-2 (HCl); 1581296-53-8 (TFA)
Molecular Weight (MW)	337.25
Formula	C16H21BrN2O
CAS No.	1184136-10-4 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 67 mg/mL (198.7 mM)
	Water: < 1mg/mL
	Ethanol: 2 mg/mL (5.9 mM)
Chemical Name	(3-Bromophenyl)[4-(1-pyrrolidinyl)-1-piperidinyl]methanone
Synonyms	UNC926 free base; UNC 926 free base; UNC-926 free base; UNC-926; UNC926; UNC 926
SMILES Code	O=C(C1=CC=CC(Br)=C1)N2CCC(N3CCCC3)CC2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50mg

available

Delivery expected until 9/6/2024