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Pregnanolone

Pregnanolone

Item no.	TMO-T19684-100mg
Manufacturer	TargetMol
Amount	100 mg
Quantity options	100 mg 200 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	Hulin MW, Lawrence MN, Amato RJ, Weed PF, Winsauer PJ. Comparison of dehydroepiandrosterone (DHEA) and pregnanolone with existing pharmacotherapies for alcohol abuse on ethanol- and food-maintained responding in male rats. Alcohol. 2015 Mar;49(2):127-38. doi: 10.1016/j.alcohol.2014.07.024. Epub 2015 Jan 6. PubMed PMID: 25620274; PubMed Central PMCID: PMC4514518.
Smiles	CC([CH]1CC[C]2([H])[C]3([H])CC[C]4([H])C[CH](O)CC[C]4(C)[C]3([H])CC[C]12C)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	128-20-1
Available
Molecular Weight	318.5
Bioactivity	Pregnanolone is a cell membrane modulator potentially for the treatment of pain. Pregnanolone is an endogenous neurosteroid that is biosynthesized from progesterone. It is a positive allosteric modulator of the GABAA receptor, as well as a negative allosteric modulator of the glycine receptor, and is known to have sedative, anxiolytic, anesthetic, and anticonvulsant effects.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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TMO-T19684-100mg-datasheet.pdf

TMO-T19684-100mg-safety-datasheet.pdf