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JND3229

JND3229

Item no.	TMO-T15615-50mg
Manufacturer	TargetMol
CASRN	2260886-64-2
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
Purity	0,98
Smiles	O=C1N(C=2C(CN1C3=C(Cl)C=CC=C3)=CN=C(NC4=CC(C)=C(C=C4)N5CCN(C)CC5)N2)[C@H]6CC[C@H](NC(CC)=O)CC6
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	2260886-64-2
Available
Short Description	JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma.
Shipping	cool pack
Storage	-20°
Molecular Weight	617, 18
Pathway	JAK/STAT signaling\|\|\|Tyrosine Kinase/Adaptors\|\|\|Angiogenesis
Target	EGFR

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T15615-50mg-datasheet.pdf

TMO-T15615-50mg-safety-datasheet.pdf