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Cenisertib

Cenisertib

Item no.	TMO-T14925-5mg
Manufacturer	TargetMol
CASRN	871357-89-0
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
Purity	0,98
Smiles	N([C@@H]1[C@@H]2C[C@H]([C@@H]1C(N)=O)C=C2)C3=NC(NC4=CC(C)=C(C=C4)N5CCN(C)CC5)=NC=C3F
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	871357-89-0, AS-703569 , R-763
Available
Short Description	Cenisertib is A potent ATP-competitive multi-kinase inhibitor, showing inhibitory effects on the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, FLT3, as well as kinase inhibitors of FER and its homolog. Cenisertib inhibits the growth of tumor mast cells (MCS) by inhibiting the activity of several different molecular targets. Cenisertib also inhibits tumor growth in pancreatic, breast, colon, ovarian and lung cancer and leukemia in xenograft models.
Shipping	cool pack
Storage	-20°
Target names or alias	AS-703569 , R-763
Molecular Weight	451, 54
Pathway	Tyrosine Kinase/Adaptors\|\|\|JAK/STAT signaling\|\|\|Cytoskeletal Signaling\|\|\|Stem Cells\|\|\|Angiogenesis\|\|\|PI3K/Akt/mTOR signaling
Target	Bcr-Abl\|\|\|STAT\|\|\|Akt

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T14925-5mg-datasheet.pdf

TMO-T14925-5mg-safety-datasheet.pdf