Comparison

Pexidartinib hydrochloride (PLX-3397)

Item no. DCC-DC31450-250mg
Manufacturer DCChemicals
CASRN 2040295-03-0
Amount 250 mg
Quantity options 100 mg 10 mM x 1 mL in DMSO 1 g 250 mg
Category
Type Inhibitors
Applications other
Specific against other
Smiles FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F.[H]Cl
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 2040295-03-0
Similar products 2040295-03-0
Available
Manufacturer - Applications
Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity.
Molecular Weight
454, 28

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 mg
Available: In stock
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