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AY-9944

AY-9944

Item no.	DCC-DC23895-1g
Manufacturer	DCChemicals
CASRN	366-93-8
Amount	1 g
Category	Cardiovascular Research Atherosclerosis Reagents & Chemicals Molecules
Type	Inhibitors
Specific against	other
Smiles	Cl.ClC1=CC=CC=C1CNCC1CCC(CNCC2=CC=CC=C2Cl)CC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	366-93-8
Similar products	366-93-8
Available
Field of Application	AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol delta7-reductase (DHCR7) enzyme (IC50=13 nM). AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol delta7-delta8 isomerase, which causes the accumulation of cholest-8-en-3beta-ol.
Molecule weight	464, 3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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