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6-Biopterin

6-Biopterin

Item no.	CS-6962-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	22150-76-1
Available
Alternative Names	L-Biopterin
CAS	22150-76-1
Purity	>98%
Formula	C9H11N5O3
MWt	237.22
Solubility	DMSO : 6 mg/mL (25.29 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Immunology/Inflammation; Metabolic Enzyme/Protease
Target	NO Synthase; Endogenous Metabolite
Biological Activity	6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor. In Vitro: 6-biopterin is extremely cytotoxic to human melanocytes under in vitro conditions. Thioredoxin reductase has the capacity to reduce 6-biopterin to q-BH2 where further reduction to 6-BH4 follows via dihydropteridine reductase or reduced glutathione. (6R)5, 6, 7, 8 tetrahydrobiopterin undergoes redox-cycling by its oxidation to quinonoid dihydrobiopterin and to 6-biopterin through consecutive two electron oxidation reactions^[1].

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