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GSK6853

GSK6853

Item no.	CS-5847-100mg
Manufacturer	ChemScene
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	1910124-24-1
Available
CAS	1910124-24-1
Purity	>98%
Formula	C22H27N5O3
MWt	409.48
Solubility	DMSO : >= 29 mg/mL (70.82 mM)
Clinical Information	No Development Reported
Pathway	Epigenetics
Target	Epigenetic Reader Domain
Biological Activity	GSK6853 is a potent and selective inhibitor of the BRPF1 bromodomain. shows excellent BRPF1 potency (pKd 9.5) and greater than 1600-fold selectivity over all other bromodomains tested. target: BRPF1.[1] In vivo: The ip route of administration would be suitable for dosing GSK6853 in potential PK/PD models. [1]

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