CASIN

Item no.	CS-5671-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	425399-05-9
Available
CAS	425399-05-9
Purity	>98%
Formula	C20H22N2O
MWt	306.40
Solubility	DMSO : >= 31 mg/mL (101.17 mM)
Clinical Information	No Development Reported
Pathway	GPCR/G Protein
Target	Ras
Biological Activity	CASIN is a selective GTPase Cdc42 inhibitor with IC50 of 2 uM. In vitro: Treatment with CASIN (5 uM) reduced the elevated level of active Cdc42 observed in aged primitive hematopoietic cells to the level observed in young cells In vivo: Reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs.

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