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Ebselen

Ebselen

Item no.	CS-5534-100mg
Manufacturer	ChemScene
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	60940-34-3
Available
Alternative Names	SPI-1005; PZ-51; CCG-39161
CAS	60940-34-3
Purity	>98%
Formula	C13H9NOSe
MWt	274.18
Solubility	H2O : < 0.1 mg/mL (insoluble)
Clinical Information	Phase 3
Pathway	Autophagy; Anti-infection; Metabolic Enzyme/Protease; NF-kappaB; Immunology/Inflammation
Target	Autophagy; HIV; Reactive Oxygen Species; Reactive Oxygen Species; Reactive Oxygen Species
Biological Activity	Ebselen is a small-molecule capsid Inhibitor of HIV-1 replication. Target: Ebselen is an organoselenium compound, as an inhibitor of HIV-1 capsid CTD dimerization. Ebselen inhibits early viral postentry events of the HIV-1 life cycle by impairing the incoming capsid uncoating process. [1] Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen is an inhibitor of inositol monophosphatase (IMPase). Ebselen permeates the blood-brain barrier and inhibits endogenous inositol monophosphatase in mouse brain. [2]

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100mg

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