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Tebipenem

Tebipenem

Item no.	CS-3444-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	161715-21-5
Available
Alternative Names	LJC 11036
CAS	161715-21-5
Purity	>98%
Formula	C16H21N3O4S2
MWt	383.49
Solubility	DMSO : >= 45 mg/mL (117.34 mM); H2O : 6.2 mg/mL (16.17 mM; Need ultrasonic and warming)
Clinical Information	Phase 3
Pathway	Anti-infection
Target	Bacterial
Biological Activity	Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa. In Vitro: Tebipenem exhibits slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin, and apparent K_m and k_cat values of 0.8 uM and 0.03 min^-1, respectively^[1]. Tebipenem shows potent activity against B. pseudomallei, with MIC₅₀ and MIC₉₀ values of both 2 mg/L^[2]. Tebipenem shows good activity against S. pneumoniae, with the MIC range of <=0.25 ug/mL in all of the S. pneumoniae isolates^[3].

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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